Jeffrey says there were times when he was "plenty sick" of writing Middlesex .
"There's no question. It did take nine years. It didn't seem like nine years I guess, you know, time flies when you're in agony," he says. "I was engrossed with the book, I was having difficulties with it, and I just didn't notice the years were going by."
The thing that kept Jeffrey going was that he'd never had such an idea before. "Usually my ideas are small. Much smaller. And this one I had such a structure pretty early on and it was a ravishing thing for me and I kept seeing it in the distance and it kept me plodding toward that goal," he says. "And every time I wanted to throw it awayI tried to simplify the book many times, tried to write it in different voices, tried to scrap itbut I just had this feeling that I did have at least the structure, and that's such an important thing in a novel that I didn't want to give it up."
Watch Jeffrey answer audience questions after the show!
Learn more about growing up intersex.