The daughter of Santa Sofía de la Piedad and Arcadio (José Arcadio III), Remedios the Beauty's beauty drives men to their deaths. She remains innocent and childlike; her mother feeds and cleans her well into her twenties. One day, she ascends to heaven in her sister-in-law Fernanda del Carpio's sheets. She is the older sister of the twins José Arcadio Segundo and Aureliano Segundo.