As a news anchor on NBC's Today Show and host of Dateline NBC, journalist Ann Curry has covered many of the top stories affecting the world today. Gayle talks with Ann about her passion for journalism, turning 50 and her aspirations for the future.

Ann's work has taken her around the globe, from covering the September 11 terrorist attacks to the genocide in Darfur and the Iraq war. Most recently, she traveled to Antarctica to follow a story on climate change, and says she has upcoming plans to bungee jump for charity. Ann says taking calculated risks are part of who she is, and that she's guided by the personal motto of, "No fear. Seize life. Step out."

Born to a Japanese mother and an American father, Ann says the hurdles she faced coming from a multicultural family only made her stronger and more determined to succeed. She credits her parents with giving her a sense of fearlessness to reach her goals, and to pursue a career of service to others. "You never ever, ever give up, especially when there's no chance of winning," she says.

Reaching her 50th birthday was a "sobering moment" in the sense that it made her more committed to making a difference. "You suddenly turn around and say, 'Okay, whatever I thought I was going to do, I better do it!'" Ann says she feels like she's 30 and hopes to live past 100. "It would be fantastic to see the future," she says. "I want to see my grandchildren. I want to see this world that we're fashioning now, that we're creating."