Dr. Oz, along with his wife Lisa and Dr. Roizen, take callers' questions and share their expertise on hot health topics. One caller who is curious about embarking on a vegan diet gets tips about meat substitutes and healthy vegan recipes. Another caller who has been diagnosed with hypothyroidism finds out which foods she should eat and which foods she should avoid to keep her condition in check. 

Then, a caller struggling with frequent urination gets tips on tackling her ailment. More concerned callers get the facts on vaccines, life after ulcerative colitis surgery and treatments for warts.