Do you have trouble saying no? Do you feel guilty, like you're letting someone down? "Many women suffer from this thing we call 'the disease to please,' which means whenever anybody asks you to do something, say something, go somewhere…many women are inclined to do so," Gayle says.


In the July 2008 issue of O, The Oprah Magazine, writer Penny Wrenn asked experts the most polite and creative ways to say no without hurting anyone's feelings for her article, "54 Ways to Say No!" Gayle talks with Penny about these stressful situations, such as splitting the check, being asked to borrow money or problems with your partner in the bedroom.