Oprah: It only gets better, let me tell you.

Charlize: I feel like my mom's life started at 50. When I look at photos of her in the late 1980s, early '90s, she is an old woman. Now she has completely come into herself.

Oprah: Is your boyfriend, Stuart, the One?

Charlize: I think so, but I don't want to put so much emphasis on it. There are no guarantees. I don't know how he's going to feel in ten years about me. Here's what I do know: Every single day I have with him, I wouldn't want it any other way. Every night when I go to bed and I get to fall asleep next to him, I wouldn't want to be anywhere else. I feel I have a family in him. The things I always wanted to share with just my girlfriends, I can't wait to tell him, too. He tells me the truth. I'm lucky.

Oprah: You keep saying you're lucky, and I can't take it. You're not lucky. You are blessed and graced. Luck is just preparation meeting opportunity. For instance, in the moment you met your manager in the bank, if you hadn't been psychologically or emotionally prepared...

Charlize: Things might have gone completely differently.

Oprah: Even the word blessed doesn't capture the bigness of it. When you are in alignment with the divine current of your life, that's when that thing people call luck happens. What do you know for sure?

Charlize: That I will die. That's the only thing that's certain.

Oprah: What makes you laugh hysterically?

Charlize: My dogs. Stuart.

Oprah: What is your greatest aspiration?

Charlize: To continue to do work that matters to me. Human beings are still so undiscovered, and I want to add to our discovery in my work. I want to bring characters like Aileen to life—to give us patience for how different we all are. If I can do that, I'll be happy.

Oprah: Are you happy now?

Charlize: Very happy. Over the moon.