Has your husband or son finally invested in a suit that fits? Donate his old ones to Career Gear, which offers unemployed men interview clothing and career counseling. Have a suit of your own to donate? The Women's Alliance provides a directory of local organizations that accept interview-ready clothing for disadvantaged job-seeking women.
Someone out there can fit into your skinny jeans. At WebThriftStore.com, you can sell old clothes, electronics, gift cards, even some cars; just post photos of each item and designate a charity you want to support with your sales.
Plenty of organizations will accept your tired attire, but Vietnam Veterans of America resells it to fund programs for veterans, and will pick up your donation.
Hold on to them until fall, then find a local coat drive through One Warm Coat (most drives begin in October). Coats must be clean, and all closures should work.