If your disorganization gets so extreme that you won't let anyone into your home or office, or if you frequently turn down social invitations to spend all your time "organizing" and "re-organizing" your stuff, consider whether you are using clutter as a protective shield—a way of insulating yourself from the outside world. It can be okay to want some private space, but living in that chaos may increase your anxiety level.
Solution: Don't organize your whole space all at once. Go slowly. Start by creating one clutter-free room in which you keep nothing but items you use and love. If the experience feels good, create another room like that, then another. Remember, an organized work or living space is a much nicer "retreat" than a cluttered one.