Botox can temporarily freeze up sweat glands in the face, hands, feet and groin. Pariser explains that the neurotoxin drug inhibits the release of acetylcholine and blocks the nerves that stimulate sweating. A dermatologist will administer the drug via multiple, quick, stinging injections. The minor pain is worth it for heavy perspirers: Most people feel completely dry for at least three or four months after the procedure.
One more thing: The amount of time it takes for sweating to return to pre-injection levels can vary, but Pariser says the majority of patients schedule another appointment within six months.