The February issue of O, The Oprah Magazine delves into the root of this problem and possible fixes, and Oprah is taking the discussion even farther. "We're opening a national conversation about hormone replacement therapy," she says. "This is about your hormones being out of whack, and you don't even know—we haven't had a language to talk about it yet."
Hormone replacement therapy is relevant to women of all ages, Oprah says. "If you're a woman who's planning to live past the age of 35, at some point you're going to face hormone imbalance," she says. "All women need to be armed with this information."