Dennis Quaid's Medical Nightmare

Every year in the United States, more people die from medical mistakes than from breast cancer, AIDS and car accidents…combined. "It's a major, major health issue that will touch almost every single American at one point in our lives," Oprah says.

In November 2007, one such mistake almost took the lives of infant twins, the children of actor Dennis Quaid and his wife, Kimberly.

Dennis and Kimberly's story begins with two small blessings, Thomas Boone and Zoe Grace. "We were so happy to be able to be blessed by those two," Dennis says. "They both came out so perfect."

Days after the twins came home from the hospital, however, they developed serious staph infections. Doctors told Dennis and Kimberly to take their newborns to Cedars-Sinai Medical Center, where they were given antibiotics intravenously.

On their second day at Cedars-Sinai, Dennis says the twins seemed to be doing well, so he and his wife went home to get some rest. That night, Kimberly says she had an overwhelming feeling that something was wrong. Dennis called the hospital to check on their children, but a nurse assured him everything was fine.

They found out later that, at the time of the call, Thomas and Zoe were actually in serious danger.