You don't have to be an MD to know the effects of an OD. Overdose on blueberry pie, and you're going to break the bathroom scale. Expose yourself to too much sun, and your skin is going to crinkle like a piece of bacon. And we all know what happens when you tip a few too many glasses of your favorite booze at the office party/happy hour/best friend's wedding.
The outer effects from the morning after: Your head pounds, your stomach churns and your whole world spins faster than a motorcycle tire. On the inside: Your liver has to work overtime to handle the OD.
While one to two drinks a day have been shown to confer many health benefits, including cardiovascular and longevity ones, upping that amount can be risky for more than the obvious reasons of decreased mental and physical abilities that come with excessive drinking. It's also because the day-after hangovers are linked to memory impairment and decreased visual-spatial skills—making you more prone to accidents even the day after a vodkafest.
Ways to prevent the hangover...besides not drinking too much!