Paul is six feet tall and only weighs 136 pounds. His wife, Meredith is 5'5" and just 111 pounds. This couple is on a mission to stop aging through calorie restriction. "Calorie restriction is eating less than would be normal for your size and weight," Paul says. The couple eats just two small meals a day—breakfast and lunch. "So they go without food for up to 16 hours," Dr. Oz says.
Dr. Oz says that calorie restriction can have longevity benefits. "We think we can actually reach life spans of 150 years with calorie restriction," Dr Oz says. However, Dr. Oz says it is far too difficult for most people to restrict calories the way Paul and Meredith do. Instead, it's important to understand why calorie restriction works and apply that knowledge to the foods you eat.
Dr. Oz explains that calorie restriction sends a message to your body that you will not be able to reproduce because there is not enough food. The body is then sent a self-preservation message. "Preserve what you've got because you can't afford to waste it," he says. Dr. Oz says there is a protein in our body called sirt that sends the same message. "It is the mother of all anti-aging proteins," he says.
According to Dr. Oz, there are certain foods that can activate the sirt protein to mimic calorie restriction. He says red wine is one example, because of the way the grapes are grown. "They grow on a hillside where life is tough, right? The plant is telling us there's a famine coming," he says. "If the plant is facing a difficult life, because it's on a hill that's dry and baked, then it's not liking life. It's going to signal to anything that eats it, 'You guys need to preserve yourself as well.' The plants are talking to us and it actually works."