Photo: David James/New Line Cinema
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After playing heartthrobs and villains for decades, John slipped into a housedress and heels to play Edna Turnblad in John Waters' 2007 remake of Hairspray. Under the brunet wig and fat suit, fans still recognize John's signature dance moves and vocals.
As Edna, the overprotective mother of a pleasantly plump teenager named Tracy, John gives heart and soul to this rolicking musical.