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Remember the One Where...? 25 Oprah Shows We'll Never Forget

O Magazine says a fond farewell. See our favorite moments, then share yours in the comments.
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Oprah talks to West Virginia resident Mike Sisco
2 of 26
Photo: Courtesy of Harpo

1987


Oprah talks to West Virginia resident Mike Sisco, a gay man with AIDS who set off a firestorm of fear and rage by swimming in a public pool. 

From the June 2011 issue of O, The Oprah Magazine
2 of 26

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