Rob Lowe and his wife Sheryl

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Rob married the woman he calls his "favorite face in the world and favorite soul," Sheryl, a former makeup artist, on July 22, 1991. The two have been married for almost 20 years.

"I'm no genius, but I'm real smart in one area. I picked the right mate, and Sheryl is my best friend," he says.

Watch Rob talk about their life in Santa Barbara Watch