Kirstie Alley first opened up on The Oprah Show about her weight battle in November 2004, when she signed on to be the spokeswoman for Jenny Craig. At the time, Kirstie told Oprah a paparazzi photo had jolted her out of denial and made her face her weight problem for the first time.

For the next two years, Kirstie followed the Jenny Craig plan and inspired people around the country to lose weight with her. Then, in 2006, Kirstie graced Oprah's stage with a new look, fulfilling a goal she'd set for herself one year earlier—to wear a bikini in public. Seventy-five pounds lighter than her starting weight, Kirstie donned a bikini for all to see.

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