I didn't hear Oprah say that before I bought the book but the first thing I did was take the cover off. I don't like messing with the covers, they always get in the way. I'm glad I did now.
From reading the reviews I knew that the story was molded to a degree on Hamlet, so the blurb on the inside flap wasn't giving much away in my opinion. The broad strokes of the uncle killing and usurping the father's place, the eventual confrontation between Edgar and his uncle was inevitable if not completely known in detail.