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Besides the obvious benefit of getting designer clothes on sale, the best part about these discount destinations is that you don't even have to get out of your pajamas to get in on the action:

Newly launched this week is Clique To Know, a flash sales website dedicated to luxury brands sizes 10 and up. You'll find high-end labels that will hug your curves in all the right places at prices you can afford. Something to note: these sales last 48 hours (and items only stay in your digital cart for 10 minutes).

One of New York City's best-kept shopping secrets is now available anywhere you can log on. Century 21--a department store and fashion destination for tourists and native New Yorkers alike--features a new set of designers online every Monday and Thursday at a major discount. Need a shopping alert? This site allows you to add future sales to your digital Outlook or iCal calendar with the click of your mouse.

Will you shop these sites? Tell us about your all-time favorite bargain.

For more great deals keep reading:

Find More Deals at Oprah.com's Great Buy of the Day.