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Cameron Diaz's New Role

Cameron Diaz in My Sister's Keeper
Actress Cameron Diaz is probably best known for her performance in romantic comedies like There's Something About Mary, Shrek and My Best Friend's Wedding. This summer, she's taking on a new kind of role, playing the mother of a cancer-stricken young girl in My Sister's Keeper. Cameron's character has dedicated her life to saving her daughter, but when she and her husband have a second daughter for "spare parts," the family faces even more emotional battles. 

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Ali Wentworth, Mark Consuelos and Gayle King, who saw a screening of the movie, say they still can't stop thinking about it. "It's agonizing," Gayle says. "You understand all points of view. It's so well done and so well cast."

From The Oprah Winfrey Show Oprah Fridays Live with Cameron Diaz